A case report: Anaphylactic reaction to chloroprocaine in a patient with mastocytosis and lidocaine allergy

Richard Hazen 1, Lawahidh Fali Hasham 2, Danielle Kirksey 2 and Ali Esmail Al-Snafi 3, *

1 Intensive Care Unit, Texas Health Alliance Hospital, Texas Health Resources, Fort Worth Texas.
2 Pharmacy Department, Texas Health Alliance Hospital, Texas Health Resources, Fort Worth Texas.
3 Department of Pharmacology, College of Medicine, University of Thi Qar.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 17(02), 292–294.
Article DOI: 10.30574/wjbphs.2024.17.3.0154
 
Publication history: 
Received on 15 February 2024; revised on 27 March 2024; accepted on 29 March 2024
 
Abstract: 
This case report presents a 53-year-old woman with a history of mastocytosis and reported lidocaine allergy who experienced an anaphylactic reaction following administration of chloroprocaine during a breast biopsy procedure. The patient was promptly treated with epinephrine, methylprednisolone, famotidine, and diphenhydramine, leading to stabilization. She was subsequently transferred to the intensive care unit (ICU) for observation and discharged after 24 hours. This case highlights the importance of vigilance and preparedness for managing anaphylactic reactions in patients with mastocytosis and known allergies to local anesthetics.
 
Keywords: 
Chloroprocaine; Mastocytosis; lidocaine; Anaphylactic reaction.
 
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